HIV- PEP (Post Exposure Prophylaxis) Access Project

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Post-exposure prophylaxis for HIV infection.

Post-exposure prophylaxis (PEP) with antiretrovirals is now widely used worldwide after either occupational contact (with blood or another blood-containing fluid), or nonoccupational contact (mainly sexual or injection-drug use). It is assumed to reduce the risk of HIV transmission by at least 80%, although its efficacy has not been completely proven. Several countries have issued guidelines to...

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Gay men’s attitudes to and perceptions of pre-exposure prophylaxis (PrEP) and post- exposure prophylaxis (PEP) Question What are gay men’s attitudes to and perceptions of pre-exposure prophylaxis (PrEP) and post-exposure prophylaxis (PEP)? Key Take-Home Messages

 There were fewer studies published on the potential use of nonoccupational PEP (nPEP) among men who have sex with men than those on PrEP.  Although 47% to 64% of men who have sex with men were aware of nPEP, fewer than 5% had used nPEP (1-3).  The proportion of men who have sex with men aware of PrEP ranged from 13% to 64% (2;4-8), but reported use of PrEP was much lower: from 0.4% to 2% (4...

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Current perspectives in HIV post-exposure prophylaxis

The incidence of human immunodeficiency virus (HIV) infection continues to rise among core groups and efforts to reduce the numbers of new infections are being redoubled. Post-exposure prophylaxis (PEP) is the use of short-term antiretroviral therapy (ART) to reduce the risk of acquisition of HIV infection following exposure. Current guidelines recommend a 28-day course of ART within 36-72 hour...

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Adherence to Post-Exposure Prophylaxis (PEP) and Incidence of HIV Seroconversion in a Major North American Cohort

BACKGROUND There is limited evidence on the efficacy of post-exposure prophylaxis (PEP) for sexual exposures. We sought to determine the factors associated with adherence to treatment and describe the incidence of PEP failures in a Montreal clinic. METHODS We prospectively assessed all patients consulting for PEP following sexual exposures from October 2000 to July 2014. Patients were followe...

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Preparing for HIV pre-exposure prophylaxis: lessons learned from post-exposure prophylaxis.

Although RCTs have not been conducted to establish the effıcacy of non-occupational postexposure prophylaxis (nPEP), studies in nonhuman primates have demonstrated protection with nPEP; observational data support the effıcacy of PEP for occupational exposures; and several studies have esablished the feasibility of nPEP delivery in various setings. Based on these data, the CDC and public health ...

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ژورنال

عنوان ژورنال: International Journal of Integrated Care

سال: 2017

ISSN: 1568-4156

DOI: 10.5334/ijic.3199